RIULS

Repository of Iasi University of Life Sciences, ROMANIA

Welcome to RIULS!

The mission of the University’s institutional repository is to manage, preserve and disseminate, in open access, the academic and institutional output of the university’s academic community. It also aims to promote values and personalities belonging to Romanian agricultural science, by storing digitized versions of rare books and manuscripts from its collections.

The repository is part of the international movement known as open science, which promotes free access to scientific literature. This translates into maximized impact of the work carried out by researchers, contribution to improving access to knowledge, increased visibility of the institution through the works of its authors and improvement of its search engine ranking.

All documents deposited in the repository receive a unique and persistent identifier called a Handle, thus guaranteeing perpetual access to scientific output through permanent links.

RIULS Repository of Iași University of Life Sciences is indexed in Duraspace, OpenDOAR,CORE,Google Scholar,BASE (Bielefeld Academic Search Engine) and ROAR (Registry of Open Access Repositories), global Directories of Open Access Repositories.

Categories in RIULS

Select a category to browse its collections.

Now showing 1 - 3 of 3

Colecții speciale - Ad Gloria Agris / Special Collections-Ad Gloria Agris 141
Cuprinde cărți și publicații periodice rare ale fondatorilor agriculturii și ai învățământului agricol românesc modern, precum și teze de doctorat din domeniul agricol de la început de secol XX.
Publicații ale Bibliotecii - Librum de libris / Publications of the Library - Librum de libris 13
Contains publications created by the Library’s staff: bibliographies, articles, tutorials, etc.
Publicații științifice ale Universității – AgriScriptum / Scientific Publications of the University - AgriScriptum 6496
Contains documents resulting from scientific research produced or edited by the departments, research institutes and study centres of the University: Doctoral Theses, articles published in ISI journals, articles published in the journals edited by the University, patents, scientific projects, etc.

Recent Submissions

listelement.badge.access-status Open Access ,
Morphometric Assessment of Pelvic Asymmetry in Domestic Cats and Dogs
(MDPI, 2026-02-27) Altundag, Yusuf; Yalin, Ebru Eravci; Bayraktar, Simge; Karabaglı, Murat; Bektaș Bilgiç, Eylem; Can Güzel, Bariș; Cherșunaru, Alexandra-Andreea; Korkmazcan, Aycan; Manuta, Nicoleta; Gündemir, Ozan; Spătaru, Mihaela-Claudia
This study used 3D landmark-based geometric morphometrics under an object-symmetry framework to quantify pelvic asymmetry in domestic cats and dogs while explicitly accounting for measurement error through replicate digitizations. Procrustes ANOVA revealed significant components of both directional asymmetry (DA) and fluctuating asymmetry (FA) in the overall dataset, and DA was further visualized as a structured, non-random pattern across the landmark configuration. Measurement error remained smaller than the FA component, yielding high repeatability, indicating that the detected asymmetry patterns were not driven by landmarking imprecision. Group-wise summaries are presented as descriptive patterns of the sample (rather than direct between-group inference). In these descriptive summaries, cats tended to show a more coherent DA pattern, whereas dogs showed greater individual variation consistent with a relatively stronger FA component; males also tended to exhibit greater FA-related dispersion than females. In regression models of FA, age showed no association, body mass exhibited only a weak trend, and sex emerged as a significant predictor, while species showed no detectable effect when covariates were included. Collectively, these results support the hypothesis that pelvic shape contains both systematic (DA) and individual-specific (FA) asymmetry components, with sex-related differences in FA magnitude, but limited evidence for age- or weight-related effects within the sampled range. The study provides a repeatable framework and baseline reference for pelvic asymmetry in cats and dogs.
listelement.badge.access-status Open Access ,
Therapeutic relevance of an EU-GMP certified Cannabis sativa L. strain in a dual in vivo model of cognitive impairment and chronic neuropathic pain
(Frontiers Media, 2026-02-20) Costăchescu, Ivona; Gogu, Raluca-Maria; Stanciu, Gabriela-Dumitrița; Solca, Carmen; Horodincu, Loredana; Szilagyi, Andrei; Crăciun,Vlad-Constantin; Ababei, Daniela-Carmen; Tamba, Bogdan-Ionel
Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and frequently co-occurs with chronic pain. Worldwide, over 55 million people are affected by AD, with nearly half experiencing persistent pain. Chronic pain has been linked to accelerated memory deterioration and an increased risk of dementia, but the interplay between these conditions remains poorly understood. Existing therapies for AD and chronic pain are limited in efficacy, highlighting the need for interventions targeting multiple pathological pathways. The endocannabinoid system, which is altered in both AD and chronic pain, represents a potential therapeutic target, though its role in AD patients with comorbid pain remains unexplored. Methods: The study evaluated the effects of an EU-GMP certified Cannabis sativa L. strain (5 mg/kg, Cannabixir® Medium Flos) on neurobiological alterations in a rat model designed to explore mechanistic interactions between scopolamine-induced transient cognitive impairment and chronic neuropathic pain induced by unilateral sciatic nerve ligation. Treatment outcomes were assessed through nociceptive tests, clinical monitoring and tissue analyses to examine cognitive and pain-related effects. Results: Cannabixir® Medium Flos induced robust, time-dependent analgesia in thermal nociceptive tests, with the combination of the Cannabis sativa L. strain, donepezil and tramadol producing significantly longer response latencies than tramadol alone. Mechanical sensitivity was minimally affected across treatments. Immunohistochemical analyses revealed that Cannabixir® Medium Flos, either alone or in combination with donepezil or tramadol, produced the most pronounced neuroprotective effects, reducing astrocytic (GFAP) and microglial (Iba1) activation, lowering Caspase-3 and IL-6 expression, and preserving both hippocampal neuronal integrity as well as peripheral nerve structure. Conclusion: These findings indicate that Cannabixir® Medium Flos, particularly when combined with donepezil and tramadol, provides superior analgesic and neuroprotective effects compared to tramadol alone. Its multi-target action - alleviating thermal nociception, reducing neuroinflammation, limiting apoptosis and preserving neuronal and peripheral nerve integrity—supports its potential as an adjunct therapy in managing dementia with comorbid chronic neuropathic pain. Future studies should explore the molecular mechanisms underlying these effects and assess long-term safety and efficacy across diverse models of neurodegeneration and chronic pain.
listelement.badge.access-status Open Access ,
Pest Des Petits Ruminants in Eastern Europe: An Emerging Threat
(Paradigm Publishing Services, 2026-04-02) Rățoi, Ioana-Alexandra; Oșlobanu, Luanda-Elena; Porea, Daniela; Maftei, Daniel Narcis; Kureljušić, Jasna; Milićević, Vesna; Kureljušić, Branislav; Vasić, Ana
Peste des petits ruminants is a highly contagious viral disease affecting small ruminants, with significant socioeconomic impact, particularly in regions with extensive livestock farming. It poses a growing threat to animal health and food security, making its surveillance and control a global priority. This review aims to assess the current epidemiological status of PPR in Europe during 2024–2025, focusing on affected countries. Official data from national veterinary authorities and international reporting systems such as ADIS and WOA H were analyzed. The review synthesizes recent trends in PPR outbreaks, concerning their timeline and geographic spread, assesses the prevention and control strategies adopted by the affected countries, and highlights challenges that encumbered effective disease management. Additionally, the paper documents clinical and pathological features observed during confirmed outbreaks in Tulcea, Romania, in 2024, providing a practical insight into the field presentation of the disease. In 2024–2025, Peste des petits ruminants re-emerged in Southeastern Europe, with confirmed outbreaks reported in Romania, Greece, Bulgaria, Hungary, and Albania. Delays in detection and insufficient cross-border coordination have significantly hindered containment efforts. While emergency measures—such as culling and enhanced surveillance—were implemented, structural or decisional ongoing challenges in veterinary systems and limited awareness among livestock owners continue to pose major challenges. Moreover, negative public responses to necessary control measures may further impede timely reporting and detection of future outbreaks. These findings highlight the urgent need for strengthening the regional cooperation and capacity-building to improve early warning systems and response capabilities. Without timely field recognition and coordinated interventions, the risk of a broader regional spread increases, threatening the EU ’s PPR-free status and undermining global eradication efforts.
listelement.badge.access-status Open Access ,
Addisonian Crisis Mimicking Acute Kidney Injury in Dogs: A Retrospective Study of 34 Dogs Diagnosed with Acute Kidney Injury in Romania
(MDPI, 2026-01-14) Roșca, Ștefania; Solcan, Gheorghe; Moroz, Mihail; Ștefănescu, Raluca-Adriana; Levința, Alina; Pașca, Paula-Maria
Primary hypoadrenocorticism (Addison’s disease) is an uncommon but potentially life-threatening endocrine disorder in dogs. Affected animals may present with clinicopathological features mimicking acute kidney injury (AKI). The challenge in diagnosing hypoadrenocorticism arises from its highly heterogeneous and non-specific clinical presentation, including acute kidney injury (AKI). This retrospective observational study aimed to evaluate dogs presenting with AKI and to identify cases in which primary hypoadrenocorticism was the underlying etiology. Thirty-four dogs diagnosed with acute kidney injury were evaluated at the Clinical Hospital for Companion Animals of the “Ion Ionescu de la Brad” University of Life Sciences, Iași, Romania, among which three (8.8%) were endocrinologically confirmed to have primary hypoadrenocorticism. The evaluation protocol included a complete clinical examination, hematological, biochemical, and hormonal investigations, urinalysis, abdominal ultrasonography, and an ACTH stimulation test. These dogs exhibited hyponatremia, hyperkalemia, a reduced sodium-to-potassium ratio, and azotemia at admission, closely resembling intrinsic AKI. Following fluid therapy and hormone replacement, rapid normalization of electrolyte and renal parameters was observed. These findings support hypovolemia and electrolyte imbalance as the primary mechanisms underlying reversible prerenal azotemia in these cases. If not diagnosed early, this condition has a significant risk of progressing to acute tubular necrosis. The findings highlight the need for careful differentiation between primary AKI and renal dysfunction secondary to Addison’s disease, as well as the importance of promptly initiating hormone replacement therapy. In conclusion, hypoadrenocorticism should be considered in dogs presenting with AKI and electrolyte imbalance. Early endocrine evaluation and prompt initiation of targeted therapy are essential to avoiding misdiagnosis and optimizing clinical outcomes.
listelement.badge.access-status Open Access ,
Fungal Contamination of Dairy Feed and Major Mycotoxin Transfer: A Risk Evaluation for Animal Exposure and Health
(MDPI, 2026-01-13) Poroșnicu, Ioana; Ailincăi, Luminița-Iuliana; Davidescu, Mădălina-Alexandra; Mareș, Mihai
This study was focused on the assessment of fungal occurrence, mycotoxin dynamics, aflatoxin carry-over, and associated biochemical responses in dairy cattle. Moisture emerged as the dominant factor for fungal communities, promoting the co-proliferation of fungal genera adapted to high water activity conditions (aw > 0.90) and antagonism against xerotolerant and xerophilic species. Aspergillus spp. dominated dry substrates (aw < 0.75), Fusarium spp. showed strong positive associations with high-moisture matrices (aw > 0.90), and Penicillium spp. exhibited intermediate, substrate-dependent behavior. Mycotoxin levels fluctuated non-linearly, independently of fungal counts: ochratoxin A (OTA) concentrations in corn silage increased from approximately 12 μg/kg at the onset of the ensiling period to >240 μg/kg at silo opening, indicating dynamic mycotoxin accumulation during storage, while zearalenone (ZEA) oscillated from 40 to 170 µg/kg. Despite the variation in total aflatoxins (AFLA-T) across feed matrices, aflatoxin M1 (AFM1) in milk remained low (0.0020–0.0093 μg/kg), confirming limited carry-over. Serum biochemical parameters—alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), total bilirubin (BIL-T), total protein (PROT-T)—remained within physiological limits, yet multivariate analyses revealed metabolic modulation linked to aflatoxin exposure. AFM1 explained >7% of the variance in serum biochemical profiles according to PERMANOVA (p = 0.002), showed significant MANOVA effect (Pillai = 0.198), and displayed a significant canonical association (p < 10−13). Linear discriminant analysis further separated Normal vs. Borderline hepatic profiles, indicating subclinical physiological adaptation to chronic low-dose exposure.