Browsing by Author "Cozma, Andreea-Paula"

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  • The 3Rs in tumor micro-environement studies: empirical bases of the ethical regulation 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    With the general goal to provide a rationale for the application of the 3Rs rule (Replace, Reduce, Refine), we aim to study the effect of the tumor microenvironment (TME) on the tumor response to a chemotherapeutic agent ...
  • Animal models for CCHFV and BSL-2, BSL-3 surrogate models 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    Crimean-Congo hemorrhagic fever virus (CCHFV) is an important tick-borne human pathogen endemic throughout Asia, Africa and Europe. The pathogenic mechanisms of CCHF are poorly understood, largely due to the dearth ...
  • Animal models: important tools for studying SARS-CoV-2 infection 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    Ever since the appearance of COVID-19, the pathophysiology of SARS-CoV2 infection, the identification of treatments and the development of vaccines have been priorities. This search for preventive and therapeutic strategies ...
  • Assessment of antibiotics sensitivity of the most frequent potential pathogen bacteria isolated in the microbiology laboratory of the Faculty of Veterinary Medicine Iași, during 2017-2018 
    Rîmbu, Cristina-Mihaela; Horhogea, Cristina-Elena; Crețu, Carmen; Grecu, Mariana; Rusu, Oana-Raluca; Cozma, Andreea-Paula; Carp Cărare, Cătălin (”Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine, Iași, 2019)
    In the veterinary practice, establishing the etiological diagnosis represents the quintessence of the anti- infectious therapy. The final diagnosis based on the correctness of the laboratory results and the microbiological ...
  • Cardiovascular consequences and Covid-19 infection: establish the model 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    Recent studies have highlighted that the risks for developing cardiovascular alterations are significantly increased in patients who previously suffered from Covid-19. This study aims at determining the functional and ...
  • Clonal dissemination of extended-spectrum cephalosporin-resistant enterobacterales between dogs and humans in households and animal shelters of Romania 
    Cozma, Andreea-Paula; Rîmbu, Cristina-Mihaela; Zendri, Flavia; Măciucă, Iuliana-Elena; Timofte, Dorina (MDPI, 2022-09-13)
    Faecal carriage of extended-spectrum cephalosporin-resistant (ESC-R) Enterobacterales in healthy pets is a concerning issue. This study aimed to determine the prevalence, genetic background, and potential for interspecies ...
  • Common European origin of Hepatitis E virus in human population from Eastern Romania 
    Porea, Daniela; Aniță, Adriana-Elena; Vâță, Andrei; Teodor, Dănuț; Crivei, Luciana-Alexandra; Răileanu, Cristian; Gotu, Vasilică; Rățoi, Ioana-Alexandra; Cozma, Andreea-Paula; Aniță, Dragoș-Constantin; Ludu Oșlobanu, Luanda-Elena; Pavio, Nicole; Savuța, Gheorghe (Frontiers Media, 2020-12-17)
    The purpose of this research was to improve the epidemiological data on HEV infection in the human population in Romania. The analysis targeted hospitalized subjects with acute hepatitis (n = 94) of unknown etiology from ...
  • Crimean-Congo hemorrhagic fever: a future health issue in France? What about Romania? 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca; Marot, Stephane ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    Crimean Congo Hemorrhagic Fever Virus (CCHFV) is the etiological agent of a severe hemorrhagic fever affecting Africa, Asia and southern Europe. In recent decades, climate change has led to an increase in the distribution ...
  • Determinarea riscului de portaj si a directiei de transmitere a enterobacteriaceelor producatoare de ESBL la animalele de companie si proprietarii acestora 
    Cozma, Andreea-Paula (2017-09-05)
  • Dogs as sentinels for West Nile virus? Iasi, Romania exposure 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca; Crivei, Luciana-Alexandra ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe, lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its discovery, WNV has caused multiple ...
  • Food safety in the age of transparency: clean label products in the post-Covid-19 era 
    Crivei, Ioana-Cristina; Crivei, Luciana-Alexandra; Cozma, Andreea-Paula; Veleșcu, Ionuț-Dumitru; Rațu, Roxana-Nicoleta; Stoica, Florina; Postolache, Alina-Narcisa ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    Clean-label products are defined as foods and beverages formulated with simple, natural, and familiar ingredients, instead of using artificial ingredients and additives. The clean label movement has gained popularity ...
  • Haematological changes in canine parvovirus infection 
    Dascălu, Mihaela-Anca; Bocăneți Daraban, Florentina; Manole, Gabriel; Cozma, Andreea-Paula; Moroșan, Șerban; Tanase, Irina-Oana ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    Canine parvovirus (CPV) infection is a highly contagious disease caused by canine parvovirus type 2 and commonly produce acute gastrointestinal illness. All dogs are susceptible to CPV, although some dogs are at greater ...
  • Humanized mouse models and human viruses 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca; Pașca, Aurelian-Sorin ("Ion Ionescu de la Brad" University of Agricultural Sciences and Veterinary Medicine, Iași, 2020)
    Well-developed mouse models are important for understanding the pathogenesis and progression of immunological response to viral infections in humans. Moreover, to test vaccines, anti-viral drugs and therapeutic agents, ...
  • Impact of recent and future climate change on vectorborne diseases: viruses analyses 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca; Crivei, Luciana-Alexandra ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    Climate directly impacts health through climatic extremes, air quality, sea-level rise, and multifaceted influences on food production systems and water resources. Climate also affects infectious diseases, which have ...
  • In vivo and in vitro models to study the mosquito-borne Usutu virus 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca; Crivei, Luciana-Alexandra ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    Usutu virus (USUV), a mosquito-borne zoonotic flavivirus discovered in South Africa in 1959, has spread to many European countries over the last 20 years. The virus is currently a major concern for animal health due to ...
  • Investigating neutrophil subpopulation dynamics in a mouse model of Sars-Cov-2 infection 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2023)
    The project largely involved studying neutrophil dynamics or kinetics in a mouse model of SARS-CoV-2 infection. The study is carried out in a mouse model using transgenic mice expressing the human ACE-2 receptor, which ...
  • Investigations on lymphocytes blastization mechanism as a result of stimulation with a specific antigen 
    Golban, Rita; Carp Cărare, Mihai; Rîmbu, Cristina-Mihaela; Guguianu, Eleonora; Carp Cărare, Cătălin; Horhogea, Cristina-Elena; Cozma, Andreea-Paula (”Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine, Iași, 2016)
    In this scientific paper are reflected the results of the investigation on the lymphocytes blastization mechanism aspects as result of stimulation with anti-anthrax antigen and protein purified derivative. The aim of the ...
  • Milk fever and related postpartum diseases in dairy cattle – a review 
    Crivei, Ioana-Cristina; Crivei, Luciana-Alexandra; Cozma, Andreea-Paula; Bugeac, Teodor; Bugeac, Celestina-Marinela ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2021)
    Milk fever is a metabolic condition that occurs in dairy cattle before or immediately after parturition as a result of low calcium (Ca++) levels in the blood (hypocalcaemia). Based on its pathological changes, milk fever ...
  • Mouse models and Sars-Cov-2 
    Moroșan, Șerban; Cozma, Andreea-Paula; Dascălu, Mihaela-Anca; Pașca, Aurelian-Sorin ("Ion Ionescu de la Brad" University of Agricultural Sciences and Veterinary Medicine, Iași, 2020)
    Since December 2019, a novel coronavirus SARS-CoV-2 has emerged and rapidly spread throughout the world, resulting in a global public health emergency. COVID-19 is causing a major once-in-a century global pandemic. The ...
  • Phytocomplex with Zingiber officinale extract, Piper nigrum and Piper cubeba oil - in vitro antimicrobial effect 
    Rîmbu, Cristina-Mihaela; Horhogea, Cristina-Elena; Neculai Văleanu, Andra-Sabina; Lungoci, Constantin; Barboi, Oana; Robu, Teodor; Cozma, Andreea-Paula; Grecu, Mariana ("Ion Ionescu de la Brad" Iași University of Life Sciences, 2021)
    Vegetal compounds are known for their therapeutic actions in correlation with their antioxidant activity so that in recent times the interest in their properties has greatly increased. The phytocomplex obtained by combining ...