Lupu, Andrei-CristianBomboș, MihaelaVasilievici, GabrielMiron, Liviu-Dan2024-05-152024-05-152019-09-15Lupu, A.C., Bombos, M., Vasilievici, G., Miron, L. (2019). 'Synthesis and Characterization of Inclusion Complex of Diminazene Aceturate with b-Ciclodextrin', Revista de Chimie, 70(6), pp. 2136-2140. https://doi.org/10.37358/RC.19.6.72912537-5733https://revistadechimie.ro/Articles.asp?ID=7291https://repository.iuls.ro/handle/20.500.12811/3903Cyclodextrins (CD) are macrocyclic biopolymers with potential applications in the delivery of small and macro-molecular therapeutic agents. Despite the potent host-guest inclusion property, their inherent lack of cellular binding ability has limited applications in drug delivery. Herein, we functionalized b-cyclodextrin (b-CD) with diminazene aceturate(DIMA), which are bioactive molecules, widely distributed some cells, and responsible for antiprotozoal activity. The inclusion complex of DIMA with b-CD was confirmed with textural, thermogravimetric, calorimetric, spectroscopic, and microscopic techniques. Thus, the proposed inclusion complex b-CD-DIMA system could be used as a site-specific drug delivery carrier.enAttribution 4.0 Internationalhttps://creativecommons.org/licenses/by/4.0/diminazene aceturateb-ciclodextrininclusion complexArticlehttps://doi.org/10.37358/RC.19.6.7291