Mărculescu, Afrodita-DoinaBejan, CodrinaMareci, DanielTrincă, Lucia-CarmenGavăt, Cristian-Cătălin2021-07-132021-07-132016Mărculescu, Afrodita Doina, Codrina Bejan, Daniel Mareci, Lucia Carmen Trincă, Cristian Gavăt. 2016. "Metabolical changes in HBV/ HIV coinfections". Lucrări Științifice USAMV-Iași Seria Medicină Veterinară 59 (4): 542-547.https://repository.iuls.ro/handle/20.500.12811/1726The aim of this study was to evaluate the main metabolic changes in the case of hepatitis B virus (HBV) / human imunodeficiency virus (HIV) coinfection. A retrospective study, on 482 HIV infected patients was assesed, at Iasi Regional HIV-AIDS Center Iasi, between 2000-2014. Subjects were divided into 2 groups, according to the presence or absence of HBV coinfection. HIV prevalence was higher in the 20-29 years aged group (86.5%), parenteral routes being the predominant mode of HIV transmission (61.5% vs 58.5%). Mean ALT levels were significantly higher (p<0.001) in the HBV group (49.92 IU/L vs 32.93 IU/L). Average total cholesterol levels were significantly higher (p<0.001) in the HBV group( 182.58 vs 167.59 mg%). The average levels of serum triglycerides in the HBV group were significantly lower (p<0.001) than those recorded in the nonHBV group (130.72 vs. 164.59 mg%). Dyslipidemia was common in the HIV/HBV coinfected group (107 vs. 82). Hepatitis B virus infection induced a 2-fold higher relative risk for the occurence of hepatic cytolysis syndrome .enAttribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)https://creativecommons.org/licenses/by/4.0/alanine aminotransferanse (ALT)dyslipidemiaHIV/HBV coinfectionhypercholesterolemiaArticle2393-4603