Trofin, Alina-ElenaOniscu, CorneliuUngureanu, Elena2024-10-282024-10-282014Trofin, Alina, C. Oniscu, Elena Ungureanu. 2014. “Synthesis of sulfochloride derivatives of the aryl oxyalkyl carboxylic acids as intermediates in obtaining compounds with biological potential”. Lucrări Ştiinţifice USAMV - Iaşi Seria Horticultură 57 (1): 19-24.1454-7376https://repository.iuls.ro/handle/20.500.12811/4753Aryl - oxyalkyl carboxylic acids and their derivatives are compounds with high biologic potential, having various pharmacological properties or auxin - type growth regulator action. The pharmacological tests determined that the presence of substituted or unsubstituted sulphonamidic groups in the phenoxyacetic derivatives confers them a toxicity which in most cases is negligible; they also have high bioavailability and can be used as effective growth stimulants for various plant species at low concentrations. Since the R1, R2 - substituted phenoxyacetic acid esters and their sulfochlorides are intermediates used in the synthesis, this paper presents the general scheme of the process for the chlorosulfonation of the considered aryl - oxyalkyl carboxylic esters, the mechanism of the reaction, the obtaining method and the sulfochlorides yields for the methyl esters of fenil-1,2- dioxiacetic, fenil-1,3-dioxiacetic și fenil-1,4-dioxiacetic acids in the reaction with the chlorosulfonic acid.enphenoxyaceticmethyl esterssulphochloridegrowth regulatoraryl oxyalkyl carboxylicArticle2069-8275