Abstract:
This study was carried out
on 68 naturally infected buffaloes with
Theileria annulata, in addition to 25
parasite-free buffaloes, distributed in small
herds at Dakahlia and Gharbya
governorates, Egypt, to demonstrate the
clinical picture associated with theileriosis,
with particular emphasis on the oxidative
stress and ketosis relationship. The clinical
signs recorded in infected buffaloes were
fever, enlargement of one or more lymph
nodes, ocular discharge, corneal opacity,
skin lesions, decreased milk yield, pale
mucous membrane and anorexia. Blood and
serum analysis revealed significant decrease
in red blood cells (RBCS) and/or
haemoglobin (HB) concentration in the
infected animals, compared to the control
ones. Moreover, a significant increase (p ≤
0.05) was found in the levels of
Malondialdehyde (MDA), beta hydroxy
butric acid (BHBA) and non-esterified free
fatty acid (NEFA) with a significant
decrease (p ≤ 0.05) in the levels of reduced
glutathione (R.GSH), superoxide dismutase
(SOD), catalase (CAT), total antioxidant
capacity (TAC), nitric oxide (NO), glucose
and glucose-6-phosphate dehydrogenase
(G6PD) in infected animals, compared to
the control ones. It can be concluded that
Theileria annulata plaid an imperative role
in the occurrence of anaemia, oxidative
stress and ketosis in Egyptian water
buffaloes.
